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Irene South Dakota
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Irene is a city in Clay, Turner, and Yankton counties in the U.S. state of South Dakota. The population was 437 at the 2010 census. The portion of Irene that is located in Turner County is a part of the Sioux Falls, South Dakota metropolitan area, the portion located in Yankton County is part of the Yankton Micropolitan Statistical Area, and the portion located in Clay County is part of both the Vermillion Micropolitan Statistical Area and the Sioux City-Vermillion Combined Statistical Area. Irene is also host to the Irene Rodeo, held every summer.
Irene was laid out in 1893, and named after Irene Fry, the daughter of a first settler.

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